Component of the SWI/SNF complex, an ATP-dependent chromatin remodeling complex, which is required for the positive and negative regulation of gene expression of a large number of genes. It changes chromatin structure by altering DNA-histone contacts within a nucleosome, leading eventually to a change in nucleosome position, thus facilitating or repressing binding of gene-specific transcription factors.

Belongs to the RSC7/SWP82 family. SWP82 subfamily.

515 amino acids

MEEEDITLEHSDDLNKEESGESNRVNIEEPEHHDNSNKESTNLDDLNMLEEPKYHDNSNKESTNLDDLNMLEEPEHHDNSKKESTNLDDSNMLEEPKHHDNSNKESTNLDDLNMSEEPKHHDSSNKESTNLDNSNMDESENQKNFKIEEPKPSGDFRNEGPKQCDDSKIEKPELHVNSKIEEPIHRIDSEHNEPEYHTESKNEESEHNTKSIREEPIHHVDSKNEEPVYSKIPEKMGDEFSENSLSKSDSAVKQEGNLLIHPNNSLKDTAPSKCKEPPVDEALSKKEISDDIAQITSVTPITEKIEDKDKYISEVIDTYGKLADGFEYRAKTFCLEGRGKVLYMLGTECSRLLGFKDSYFMFHKTPSLRKVLTTQSERDQMVEMGLLASNFRFRQLSIVPARQMFLAFGARILMKGTIDPESHKALIEKNISWADDEYYHMDVMANGSTRSSSVKLELKSMDNQNSPSPFQGKDILTLAQGASFYNSKVMRTRNLRKEARLSYYTKLRGVNRSVS

59 kDa

(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)

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