In vitro binds long double-stranded RNA (dsRNA) (500 and 700 base pairs), but not dsRNA shorter than 300 bp. Not involved in RNA autophagy, a process in which RNA is directly imported into lysosomes in an ATP-dependent manner, and degraded.

Belongs to the SID1 family.

831 amino acids

MLDCPRLALLCALPWLLRAAVPGHRAEPLKRSAELPRNPRDPARGADFDRVYSGVVSLSTENIYSFNHTSHPGQVTAVRVHVNSSSDNLDYPVLVVVRQQKQVLSWQVPLPFQGLYQRSYNYQEVSRTLCPSKATNETGPLEQLIFVDVASMAPHGAHYKLLVTKIKHFQLRTNVAFYFTASPSQPQYFLYKFPEDVDSVIIKVVSEKAYPCSVVSVQNIMCPVYDLDHDVEFNGVYQSMTKQAAITLQKDFPDEQFFVVFVIKPEDYACGGSFSIQENENQTWNLQRSKNLKVTIVPSVKGSVYVKSSLFSVFVFLSFYLGCLLVVFVHHMRFQRKPVDGSFGSGDGSGNMAVSHPITASTPEGSNYGAIDESSSSPGRQMSSSDGGQPCHSDTDSSVEESDFDTMPDIESDKNVIRTKMFLYLSDLSRKDRRIVSKKYKIYFWNIITIAVFYALPVMQLVITYQTVVNVTGNQDICYYNFLCAHPLGVLSAFNNILSNLGHVLLGFLFLLIVLRRDLLHRRALEAKDIFAMEYGIPKHFGLFYAMGIALMMEGVLSACYHVCPNYSNFQFDTSFMYMIAGLCMLKLYQTRHPDINASAYSAYASFAVVITLTVLGVVFGKNDVWFWIIFSAIHVLASLALSTQIYYMGRFKIDVSDTDLGIFRRAAMVFYTDCIQQCSRPLYMDRMVLLIVGNLVNWSFALFGLIYRPRDFASYMLGIFICNLLLYLAFYIIMKLRSSEKVLPLPVFCIVATAVVWAAALYFFFQNLSSWEGTPAESREKNRECVLLGFFDDHDIWHFLSATALFFSFLVLLTLDDDLDVVRRDQIPVF

94.1 kDa

(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)

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