Does not possess a ribonucleotide reductase activity. Betaherpesviruses probably use another strategy to expand the dNTP pool in a quiescent host cell.

Belongs to the ribonucleoside diphosphate reductase large chain family.

906 amino acids

MNPADADEEQRVSSVPAHRCRPGRIPSRSAETETEESSAEVAADTIGGDDSELEEGPLPGGDKEASAGNTNVSSGVACVAGFTSGGGVVSWRPESPSPDGTPSVLSLTRDSGPAVPSRGGRVSSGLSTFNPAGATRMELDSVEEEDDFGASLCKVSPPIQATRMLMGKKCHCHGYWGKFRFCGVQEPARELPSDRNALWREMDTVSRHSAGLGSFRLFQLIMRHGPCLIRHSPRCDLLLGRFYFKANWARESRTPLCYASELCDESVRRFVLRHMEDLPKLAEETARFVELAGCWGLYAAILCLDKVCRQLHGQDESPGGVFLRIAVALTAAIENSRHSRIYRFHLDARFEGEVLESVLKRCRDGQLSLSTFTMSTVGFDRVPQYDFLISADPFSRDASWAAMCKWMSTLSCGVSVSVNVTRLNADVNSVIRCLGGYCDLIREKEVHRPVVRVFVDMWDVAAIRVINFILKESTSELTGVCYAFNVPSVLMKRYRAREQRYSLFGRPVSRRLSDLGQESAFEKEYSRCEQSCPKVVVNTDDFLKKMLLCALKGRASVVFVHHVVKYSIMADSVCLPPCLSPDMASCHFGECDMPVQRLTVNVARCVFARSDEQKLHLPDVVLGNTRRYFDLSVLRELVTEAVVWGNARLDALMSASEWWVESALEKLRPLHIGVAGLHTALMRLGFTYFASWDLIERIFEHMYFAAVRASVDLCKSGLPRCEWFERTIYQEGKFIFELYRLPRLSIASARWEALRADMLEFGLRNCQFLAVGPDDEVAHLWGVTPSVWASRGTVFEEETVWSLCPPNRECYFPTVVRRPLRVPVVNYAWLEQHQEEGKATQCLFQAAPAIQNDVEMAAVNLSVFVDQCVALVFYYDSGMTPDVLLARMLKWYHWRFKVGVYKYCAS

101.7 kDa

(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)

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