Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs.

Belongs to the RNase E/G family. RNase E subfamily.

968 amino acids

MKRMLINATQQEELRVALVDGQRLYDLDIESSRSEQKKSNIYKGKITRIEPSLEAVFIDYGMEKHGFLPLKEISKNYFPENYNCDVRLNIKDILREGQELIVQINKEERGTKGAALTTFITLAGSYLVLMPNNPKIAGISRRVEGSDRIELKELLSSLKIPEKMGLIIRTAGVGKSIKSLQWDLSLRLKHWNAIKKASKKKSAPFLIYQESNVIVRAFRDYLRQDIGEILIDNPKILDIAREHITALGRPDFINKIKLYTGEIPLFSYYQIESQIDSAFQRKVRLPSGGSIMVDTTEALTAIDINSSRSTRGADIETTAFNTNLEAVEEISRQLRLRDLGGLIVIDFIDMTTISHQKIIENKLREIVREDRARIQIGHISKFGLLEMSRQRLSSSLGESSHHICPRCTGTGTIRDNESLSLSILRLIEEEALKENTYEVHAIVPIEIACYLLNEKREAVYAIEKRQAGGKTIIVPNKNMKTPHYLVSRIRKGEQIRSMSYCLSNVRKNKIFNNIKKEIVDKKHKLNSTLTNISLSDDSFDKQKEEKEKFLRKKNYNNSIINALFNNKNLFFKFIVWIKNSFLKKHIFVKNESFKRNIFQNKKNILFAKKEEFNSIEEIHKKDNQVSSIDNNKKKQLLNKVKKNNNHQYSHVFDNNTKYTSLKKIDFQKNTIDFELNSLNFLKKNNFYIFSKYNFLYTKKYAKNKFKDFENIKSQNDMICYESFQKDLENNTSFKKKLLYNIIFNNCYPNNILVNINSTIFQIYKNSEFFKFFPIKISILMTPLNIFSLELILEPSSKKCSSFKENQVKKRLRINNYKKLNSSFIHKKNNFVKNSVLWPKKFTTEEIKINHLYKKNKKNTKSYFFETSFKYKTVTKNISKLKVKLTSKKNDYLISNQKKLFLNKTLKKENTKNKSSAPITKIFSDVFLSKNQKIMNSSIFLKKSNKKIKNSAGAHSATNFSTSPVKKSE

112.7 kDa

(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)

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