Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RAR/RXR heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5 (By similarity).

Belongs to the nuclear hormone receptor family. NR1 subfamily.

505 amino acids

MMKFSDTASCRDGGERPEEEGKGAGGRSKLRMGKEEFTGSVGKEEAAAVASMSSSKDRICSTSTQLSQLHGFPPSMYPFAFSSNMRGSPPFDLTNGGAYFRSFPTDLPKEMASLSVETQSTSSEEMVPSSPSPPPPPRVYKPCFVCNDKSSGYHYGVSSCEGCKGFFRRSIQKNMVYTCHRDKNCQINKVTRNRCQYCRLQKCFEVGMSKEAVRNDRNKKKKEIKEEVVTDSYEMPPEMEALIQKVSKAHQETFPSLCQLGKYTTNSSADHRVQLDLGLWHKFSELATKCIIKIVEFAKRLPGFATLTIADQITLLKAACLDILMLRICTRYTPEQDTMTFSDGLTLNRTQMHNAGFGPLTDLVFAFAEQLLPLEMDDTETGLLSAICLICGDRMDLEEPEKVDKLQEPLLEALKIYARRRRPNKPYMFPRMLMKITDLRGISTKGAERAITLKMEIPGPMPPLIREMLENPEAFEDDASPPPKSEQKPIKVEEKPGEKTSTKDP

56.6 kDa

(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)

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