Regulator of biological processes that recruits a histone deacetylase to control gene transcription. May play a role in the entry into mitosis, negatively regulating the cell proliferation. Formation of stable complexes with geminiviridae replication-associated proteins may create a cellular environment which favors viral DNA replication (By similarity).

Belongs to the retinoblastoma protein (RB) family.

1035 amino acids

MSPAALKNMEENKTTVMTTSHSSNDGGETVKGYSDAVEVRFSDFCKSGLALDENTCTQAIKLFKDTKHLLMTNVSSIGNGTSEEAERFWFAFVSYSVKRLSEKNRDDAQQKSDDPGLTLCQILRLAKLNIVDFFKELPHFIVKAGPILSNIYGADWENRLEAKELQANFVHLSILSRHYKRACRELFLTSDASSDKQPAISNEATHVSDHHRFGWLLFLALRVHAFSRFKDLVTCTNGLVSVLAVLIIHVPVRFRNFSFNDSQWFVRKGDKGVDLLASLCNKYDTSEEVLRKSMETTNNLIANILKKKPHSASEYKNENLVNINPDGLIYYEDLMEESSLQSSLNILEKDYDDAIRNKAELDERVFINEEDSLLGSGSVSAGSLNITGAKRKFDLISSPTKTITSPLSPHRSPASHANGIPGSANSKMAATPVSTAMTTAKWLRTIISPLPSKPSAQLERFLVSCDKDVTNDVIRRAQIILEAIFPSSSLGERCVNGSLQSTNLMDNIWAEQRRLEALKLYYRVLESMCTAEAQILHATNLTSLLTNERFHRCMLACSAELVVATYKTVTMLFPAVLERTGITAFDLSKVIESFIRHEESLPRELRRHLNSLEERLLDSMVWEKGSSLYNSLTVARPALSAEINRLGLLAEPMPSLDAIAMHINFSSGCLPPVPSLQKHETSPGSGQNGDLRSPKRPCTDFRSVLVERNSFTSPVKDRLLGNLKSKLPPPPLQSAFASPTRPNPGGGGETCAETGINVFFTKINKLAAVRINGMIEKLQPSQQHIRENVYRLFQLILSHQTSLFFNRHIDQIILCCFYGVAKISKLNLTFREIIYNYRRQPHCKTLVFRSVFVDWSSARHNGRTGQDHVDIITFYNEIFIPAAKPLLVDVGSAGTTVKASNVPEVGNNKDGQCPASPKVSPFPSLPDMSPKKVSSAHNVYVSPLRSSKMDALISNSSKSYYACVGESTHAYQSPSKDLNAINNRLNGNRKARGTLNLDNDVGLVSDSMVANSLGLQNGNCASTSGAALKSEQSDS

114.6 kDa

(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)

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