Guanylate cyclase involved in the production of the second messenger cGMP. Regulates chemotaxis responses toward salt ions in ASE sensory neurons (By similarity).

Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.

1135 amino acids

MTQLLRFLLILSIFCDFSHSQRPTIRVGIAAALKTQNGSIGWAYAGGAVPLALQYLKSHGFVKDFDFEFHVEYTECDLTETVRAGLDFMKTKNYDVIIGPPCATPLIAMGTLSTVYKKPVLGWGFVSESEFSDMERFPYLTSVLPSSMTLGTVTSALLELYGWDRIALVYFKNELNYCSGVIEDVETSLYDENYSQMVQVVIKEEVDQNNTENFVATLQMIKARARIIIFCAQTGAEKRFYMIQAGKQGMNTSEYVHVMLSMRSVGFGVQSAVGKKPLNSGLAPIWEAFQVAPDGLEDLAKSVASKMLVIDLSSDIRDKEFLQYMTKNIVYAIREPPLSCMAPECLAANATGMGAYARHLFDVFYMYGMALTNLNSTDPNIYGNVDLLVSKFTTPFEGMTGQVQLNSELSRLPLYQVYALNKEYDQISIMNISLINGTAKVSLAYQNESSDVWHFWGSTRPLDTPICGFLGKSCPIPFFDQYRLLIFVFVIVAGLLILAIFTCLTSMVRNQRAEQSRLNSEWQIHAIKLRIPEKKGRRLSTDSENSTVTKSSKGSSSKNFETSEFNENYEIQFLENDLVLTTAHQVQELSNLDKMRLVKLRKLDHENLNKFIGLSIDGSRYLAVWKMCTRGSIQDIMSRGNFSMDYFFMFCMIRDIAEGLNFLHKSFLRLHGNLRSATCLVNDSWQVKLAEFGLEFLQDDEERPTQKRLLWAAPEVLRGSLTVSQMDPSADVYSFAIVASEILTKKEAWDLHKRKEGYEGKRGNSKIEIIYNVKKGGPHPFRPTLLTDSDVNKSLLALVKDCWSENPEARPNTENICKIILDMTPRTKDNLMDHVFSMLEEYTQTLEVEVDERTKELVLEKKKSDILLGRMLPKQVAERLKAGQAVEPESFDLVTVFFSDLVKFTELANKCSPFQVVNLLNEVFSNFDAIIEKHDVYKVESIGDGFLCVSGLPNRNGVEHIRQIVEMALGFLEFCDKFRIPHLPRERVELRVGVNSGSCVAGVVGLSMPRYCLFGDTVNTASRMESNGKASLIHMSEIAHAFLVDHFPYQYETNSRGEVIIKGKGVMETFWLLGRISMSNRSTPPVAQLKQLPQKCSSFTDTGTIRSVSPYIENASDSEDEELRRVMRREMMRVS

128.3 kDa

(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)

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