Negatively regulates stress-induced JNK activation and apoptosis by promoting MAP2K7 phosphorylation and inhibiting its ability to activate JNK. Following prolonged stress, anti-apoptotic effect stops because of degradation of RASSF7 protein via the ubiquitin-proteasome pathway. Required for the activation of AURKB and chromosomal congression during mitosis where it stimulates microtubule polymerization (By similarity).

359 amino acids

MVLELVAMELKVWVDGIQRVVCGVSEQTTCQEVVIALAQAIGQTGRFVLVQRLREKERQLLPQECPVGAQATCGQFANDVQFVLRRTGPSLSGRPSSDNCPPPERCPVRASLPPKPSAIPGREPRKALTFNLRCPKLVPSPSIPEPAALVGPIPDGFADLQDLELRIQRNTEELGHEAFWEQELQREQAREREGQARLQALSAATAEHAARLEALDAQACALEAELRLAAEAPGPPSATASAAERLRQDLATQERHSLEMQGTLALVSQALEAAEHALQAQAQELEELNRELRQCNLQQFIQQTGAALPPPPPQLDRTIPSTQDLLSPNRGELQGVPQSHILVSSLSPEVPPMRQSSWR

39.2 kDa

(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)

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