Description
Protein kinase that participates in the induction of vulva and has a role in fertility and viability. Acts downstream of the Ras protein let-60. Required for progression of developing oocytes through the pachytene stage. Positively regulates lifespan upstream of mek-2 and mpk-1.
Family
Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. RAF subfamily.
Species
Caenorhabditis briggsae
Sequence
MSRINLKKSSAATTPTSPHCPSPRLISLPRCASSSIDRKDQGSPMASPSTPLYPKHSDSLHSLSGHDHSGVGTSDKEPPKFKYKMIMVHLPFDQHSRVEVRPGETARDAISKLLKKRNITPQLCQVNTSPDSKTEAIDLSKTMEEIALHLPDNELWVHSEYLNTVSSIKHAIVRRTFIPPKSCDVCNNPIWMMGFRCEFCQFKFHQRCSSFAPLYCDLLQSVPKNEDLVKQLVGIASENDGPDRSVAEIVLAGLAPTYGQSPAATPDSSHPDLTSIKRTGGVKRHPLAVSPQAETAQLSPAGPYPRDRSSSAPNINAINDEATVQHNQRILDALEAKRLEEESKDKTGSLLSTQARRPHCYSGHILSGSRMNRLHPLVDCTPLGSNSPSSTCSSPPGGLMGPTLLGQSSSVSGSTTSSLVAAHLHTLPLTPPQSAPPQKISPGFFRNRSRSPGERIEAQRPRPPQKPQHEDWEILPNEFVIHYKVGSGSFGTVYRGEFFGTVAIKKLNVVDPTPSQMAAFKNEVAVLKKTRHLNVLLFMGWVREPEIAIITQWCEGSSLYRHIHVQEPRVEFEMSAVIDILKQVSLGMNYLHSKNIIHRDLKTNNIFLMDDMSTVKIGDFGLATVKTKWTVNGGQQQQQPTGSILWMAPEVIRMQDDNPYTPQSDVYSFGVCMYEILSSHLPYSNINNRDQILFMVGRGYLKPDRSKIRTDTPKSLMKLYDNCIMFDRNERPVFGEVLERLRDIILPKLTRSQSAPNVLHYDSQYSVMDAVMRSQMVSSSYIPPSTAKTPQSAAAAAAANKKAYYNVYGLI
Simulated SDS-PAGE

(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)
Safety
Upon ordering, we will perform rigorous biosecurity and export control screening to ensure that order fulfillment is consistent with all legal and regulatory guidance.
Protein synthesis service