Plays a role in membrane trafficking and in homotypic early endosome fusion. Participates in arteriogenesis by regulating vascular endothelial growth factor receptor 2/VEGFR2 cell surface expression and endosomal trafficking. By interacting with SDCCAG8, localizes to centrosomes and plays a critical role in ciliogenesis.

Belongs to the rabaptin family.

585 amino acids

MAAAAPAAAGEDGRRRLPGAALDIQPQEGAKVEAESGELERLRAELAGALAEMETMKAVAEVSESTKAEAVAAVQRQCQEEVASLQAILKDSISSYEAQITSLKQERQQQQQDCEEKERELGRLKQLLSRAHPLDSLEKQMEKAHEDSEKLREIVLPMEQEIEELKAKLLRAEELIQEIQRRPRHPPSLHGSTELLLSRDPSPPLEPLEELSEDGGPAAEAFAHNCDDSASISSFSLGGGASGRASLPRSRQGLSPEQEETASLVSTGTLVPEGIYLPPPGYQLVPDNQWEQLQLEGRQLQKDLESISRERDELQEGLRRSNEDCAKQMQVLLAQVQNSEQLLRTLQGTVSQAQERVQLQMAELANSHKCLSHEVKRLTEENQGLRAEQPSSSVPRVLEQDEGWEESLPSSLPELQQLVRRTQQEARARQQAQEHEAERLRIEIVTLREALDEETAARASLEGQLRVQREETEVLEASLCSLRMEMERVQEEQSKAKRQEVLRPSQGTGRTEEAQLTDLLSEQRAKMLRLQAELETSEQVQRDFVRLSQALQVRLERIRQAGSLEQVRGIIDEAPLRDVRDIKDT

65.6 kDa

(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)

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