RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity). Contributes to long-term survival under nutrient deprivation, to stationary phase-dependent hydrogen peroxide and acid stress resistance and is required for prolonged survival in the intracellular environment of the host macrophage. Therefore, contributes not only to a generalized stress response in stationary phase but also to pathogenesis in mice, allowing the brucellae to adapt to the harsh conditions encountered within macrophages.

Belongs to the Hfq family.

78 amino acids

MAERSQNLQDLFLNSVRKQKISLTIFLINGVKLTGIVTSFDNFCVLLRRDGHSQLVYKHAISTIMPSQPVQMFEGEEA

8.9 kDa

(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)

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