Description
Functions as a calcium- and DAG-regulated nucleotide exchange factor specifically activating Rap through the exchange of bound GDP for GTP. May function in cell aggregation and adhesion.
Family
Belongs to the RASGRP family.
Sequence
MDSSDLDKGLTIDDIVVKCIQSFDKDGKLSDPEFVQMFLMMHPWYIPSGDLAKKLSALSESGDNVERERICQLVRFWISEFPAEFDLNPELGEQIRDLKRALENKGNRRESNLIDIESVPSYGWKRQVTQRGPSGGRVRKTSLLFDHLDPAELAEHLTHLEFHSFSKILFQDYHSFVLHGCTVGNPVLERFIALFNGVSQWIQLMVLSKHTPQQRAAVIKQFVQVAEKLLQLQNFNTLMSVVGGLSHSSISRLKDTQSHISPETTKVFDSLLELLTSSDNYARYRRRFATCEGFHFPALGVHLKDLMALHVALPDWADKAKTIINISKMRQVYKVVHELTEAQRLEPPVKANPDLLNLLTVSLDQYRSEEEIYQLSLQREPRARTTQTNAKSPPSPSPPLEEWASLKAKPDQALLCQHIEKMVESVFRLFDEDGDGHISQEEFQSVRSNFPYLCAFNEIDQNHDGKISKQEMTSYFQRASSVLDCKMGFIHNFAERTFLRPVSCQHCGNLILGIYKKGLKCRACGITCHKHCKDHLSIECKKRSKSVSERGESMEKGRHFSFTLPRSFRRSTLYPDLREEEPQLEEDGVFDDRL
Simulated SDS-PAGE
(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)
Safety
Upon ordering, we will perform rigorous biosecurity and export control screening to ensure that order fulfillment is consistent with all legal and regulatory guidance.
Protein synthesis service