Involved in regulation of membrane traffic between the Golgi and the endoplasmic reticulum; the function is proposed to depend on its association in the NRZ complex which is believed to play a role in SNARE assembly at the ER. May play a role in cell cycle checkpoint control. Essential for telomere length control (By similarity).

Belongs to the RINT1 family.

792 amino acids

MLAADDIGEVPAAPCCPESGDETKNTDVKSDVNTAAPAGSEQLSQGGSDDALLSYVSAFIEKEVGSDLKSLKTLGKLIEQMTESKVKLEEQVLTISSEIPKRIQSALKDAEESKQLLDEFLEQEAPLFSSISSHLLMAQPWMDDLGAMITQMEEIERHLAYLKWVSQTEELSDNIQQYLMTNSVPEAASLLVTMTELDIQLQESSCTHLLSFMRATVKFWHKILKDKLTSDFEEVLAQLHWPFTSHTQSQTVGGSRPAGTPELYSSLDTLFCQLLKLQASDELLTEPKQLPEKYCLPASPPVTLPIQVMLAPLQKRFRYHFRGSRQTNVMSKPEWYLAQVLMWIGNHTQFLDEKIQPILDKVGSAVNARLEFSRGLVMLILEKLASDIPCLLYDDSLFCHLVDEVLLFERELHTVHGYPSTFASCMHILSEETCFQRWLTVERKFALQKMDSMLSSEAAWVSQYKDISDVDEMKVPDCAEVFMTLLLVITDRYKNLPTASRKLQFLELQKDLVDDFRIRLTQVMKEETRAALGFRYCAILNAVNYISAVLADWADNVFFLQLQQAALEVFAENNVLSKLQLGQLASMESSVFDDMINLLERLKLDMLTRQVDHVFREVKDSAKLYKKERWLSLPSQSEQAVMSLSSSACPLLLTLRDRLLQLEQQLCFSLFRIFWQMLAEKLDLYIYQEIILANHFNEGGAAQLQFDMTRNLFPLFSHYCKRPENYFKHVKEACIILNLNIGSALLLKDVLQSVSEHIPATAALNEVGVYKLAQQDVEILLNLRTNWPNTGK

90.1 kDa

(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)

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