Non-catalytic subunit of the queuine tRNA-ribosyltransferase (TGT) that catalyzes the base-exchange of a guanine (G) residue with queuine (Q) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).

Belongs to the queuine tRNA-ribosyltransferase family. QTRT2 subfamily.

417 amino acids

MKFVIESLTKNSGRLGRLHIKDGAPGQRTPLLMQTTKGGSIPYLSADVFESHVTETPQLLELTLSTIDHMSEALAQFNSADRGLSDYIGFPGHLNVLLLRDPCETTPAGGNDRDIQPLFTRRGKESLSPKRYMEMVASLRPDIYQGLCDADTNAESAKKRVQKSVDRTEKFMHYIYEHKSKVDSTLLAPIVGGYNTFARTQSIKHALEQPSGSYGGYVFEGFHTNGLSATILDASKLLPIVEHCVGQLEEEKPRMVPGAYTPLTTLELIGLGMDLFDTSYAYCAAVNFKALTFTFVQDEVVHVPFLDITDDAIKEDFSPLLKNCVCLSCQKHTRAYVHHLYKTNELLGPILLMVHNLHHYMAFFEAIRESIARDGLPQLTELVRRQNGDSQVDYSIAPNRKVISKATMGKGFAAAAV

46.3 kDa

(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)

Upon ordering, we will perform rigorous biosecurity and export control screening to ensure that order fulfillment is consistent with all legal and regulatory guidance.

Make GL17966 using our protein expression services starting at $99 + $.30/amino acid in as fast as two weeks (includes the cost of DNA synthesis)

Order Here