Description
May catalyze the biosynthesis of dTMP using an unknown cosubstrate. In vitro, also catalyzes the dehalogenation of 5-bromo-deoxyuridine monophosphate (Br-dUMP) and the tritium exchange of [5-3H]deoxyuridine monophosphate ([5-3H]dUMP).
Family
Belongs to the thymidylate synthase family. Archaeal-type ThyA subfamily.
Species
Methanothermobacter marburgensis (strain ATCC BAA-927 / DSM 2133 / JCM 14651 / NBRC 100331 / OCM 82 / Marburg)
Sequence
MAYEISVDEIAEGWLKLVEKIMSDGREIRDERGSLTREVMNTVVTIKNPLGRSGDFYHLPARSLINIRVPEGYFWSGEKLEKYSEQFLSDDRKGFVYTYGNRLRAHFGVDQVDRAIERLKNCKESRRATMVTWDPKIDTESDEVPCMILVDFKVREGRLFTTALWRSHDIYGAWFPNAVGLAYLADHVASEVGVEVGHITIHSISAHIYEVNFKEAKEVIKNG
Simulated SDS-PAGE

(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)
Safety
Upon ordering, we will perform rigorous biosecurity and export control screening to ensure that order fulfillment is consistent with all legal and regulatory guidance.
Protein synthesis service