Description
Catalyzes the condensation of alpha-ketoglutarate and acetyl-CoA to form trans-homoaconitate. Can also catalyze the condensation of alpha-ketoadipate with acetyl-CoA to form (R)-homo(2)citrate, and the condensation of alpha-ketopimelate with acetyl-CoA to form (R)-homo(3)citrate (By similarity).
Family
Belongs to the alpha-IPM synthase/homocitrate synthase family.
Species
Methanosarcina mazei (strain ATCC BAA-159 / DSM 3647 / Goe1 / Go1 / JCM 11833 / OCM 88)
Sequence
MSESEQYSRNTLMDFIDYRPLDIEICDVTLRDGEQTPGVVFSKEQKLAVASELDSMGIEVIEAGFPVVSADEKEIVKEIANQGFNSRICCLSRAVKGDVDAALECDVDIVSIFIAMSDMHLKYKYHRSLEDMLGCAKEAIEYATDHGLKVRFAAEDASRTPVERLKQAFKEVENEYKVQYVSLADTVGILNPTTTNYLVSEIFKSVNTAICIHCHDDLGMATANTLAAAEAGAKQLHTTVNAIGERAGNASLEEVLVALRVQYGIERYDTTKLNSLSEMVSEYSGITPSVNKAVVGKNAFTHESGIHVAAILEEPRTYELFLPEMVGGKRNLVVGKHTGKKALKGIINSIGFCLEREELCALIEKVKVCTEEKHKSISRDQLERLITQVKQEQKPSGSEKEKFSI
Simulated SDS-PAGE

(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)
Safety
Upon ordering, we will perform rigorous biosecurity and export control screening to ensure that order fulfillment is consistent with all legal and regulatory guidance.
Protein synthesis service