Protein expression services for pqe-1 | Putative RNA exonuclease pqe-1
Description
Putative RNA exonuclease which protects neurons from the toxic effects of expanded poly-Q disease proteins (PubMed:12486229). It is unknown whether this is via participation in the pathogenic mechanism underlying poly-Q-induced neurodegeneration or if it is by acting as a genetic modifier of the age of onset or progression of neurodegeneration (PubMed:12486229). Regulates gene expression in neurons (PubMed:22870397).
Family
Belongs to the REXO1/REXO3 family.
Species
Caenorhabditis elegans
Length
1647 amino acids
Sequence
MFNGGYGSGNSFNLQNYAPIDPMTGIPGFGPSQNAQQQQQQASAPGTSSGGPSQAVSGASSGASMKTEPVARQVSTAQMKRDLEQAAVYVPTPIPEGSTQPQQRQQQQSQPQARQMSTQQAANLRKNAAAAGTPPKQAMQGASREQGNAHQPTAGQIPQSSNQPAQQTHNVPRMPQPLQQVPHPSPVRGSHPAAQQVQNAPQRIPQHVPMPQGVAPHQVIQQVRAPNIGASQMVQQAPSRGHTGAAPASRMAQQPVPLHQGVAPHQAAPQTIQQTPARGRPANAQLAQNAQQRNPQQVPMPQGVAPHHIPPQALGPHGAAPQMTQQAPARGPSGAAQHAQNAHRMTHQQVPLQAPVQGPHRGAPQMAQQPGPHGAAQHPSSGTVAPMHITSLPGNHPLNRTHLLFNRQVVPALDIRNLIAQHRLMVDDFVRAQICYRLPENHQDYWPPGGHPIPMQQQQMRQGAGLPNMAMPPPPLMRHPGPHQNPIHAMQSMQVQPPLSPDQMNMQMFQQRALMMQQQAMQMQMQNPPPVHQQPPPQQPPQQQRQKQQRSQPAPARVPPQVPSQVPVTGGVAADEPPPPCSYSPVAQSSESKIEPVDVKPRVAPVPPQVPVTPTKPVITNNKKKRIDVVTLDEDAPRRVQVKQEIPEVSSTSDATKSDAAPTARGAVRIKQEVESDVAPNTILISAKKFERMKAEAEDKEDMKKKIAALQEALFNIQEERRVEKEIAAFATTNQAVPQNQPASSVQIAQVSTSESDAPGTSEAAATETMTSPKTKNNVIVETEGEQEEDEDEIPIKKSKKRRAKIVSNDEEEEPVRHPKRRSDEKREKRHVSYAESDDDMPVVKKKRRNQSPEDPEYSAASPSEDEDDDIGSFVVSDNEDDDADSFVVGDDEPIEYEEEDEDDMIERRSSRKRRSDSRSKKSATPTDRRRSRDTPTGSRSMRSTSPNDRRKSRETPPGNRSMRRTSPSDGRKSRDTPTASSSMSSSTLSYCKKSKETPMSYEEIEQQKKAKRQRNCKTREENRERKRLAQLEELESSETTGVRRTLRSTQDNSDPLDASLATTIEEFRKTKKKDAKSSENRAKEKQKPMNKRPTSSASVDSNDDGVHIPAKRMAHASSVPGPSRSKPPMIGAVKNRPNHTEMLDKRNKESEEKRRKDRDELERLRNKKHTTEEEKIKMARLQNALKVVGKAAGLKATVKKELTGSPAKKQKPAPAVPKILDFSVGRTFTAIRQTAIKLVFDTFLERDSPNAAREAQEFELSIAKQYTDGQKYRINIGHKVAALRKENTSGILEVNKNAVSHDKILAGGPKDNCTVARGRKTHVDHRQLSIEKLHPLLLQFKLTTSELETNAYPMRRDGSTKAVSIADTVYTQNKKMFLDDYDMSRNCSRCNKEFKLSPNGTMIRSTGICRYHNRGVAINGKRDTFRKRYSCCNEEFNVALGCKFSDVHVTDQLFKKELSTFVSTPVPVPNDQRSTRVYALDCEMVYTIAGPALARLTMVDMQRNRVLDVFVKPPTDVLDPNTEFSGLTMEQINSAPDTLKTCHQKLFKYVNADTILIGHSLESDLKAMRVVHKNVIDTAILFRSTRDTKVALKVLSAKLLHKNIQGDNEDAIGHDSMEDALTCVDLIFYGLRNPESIAIREANTNC
Mass
182.3 kDa
Simulated SDS-PAGE
(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)Safety
Upon ordering, we will perform rigorous biosecurity and export control screening to ensure that order fulfillment is consistent with all legal and regulatory guidance.
Protein synthesis service
Make pqe-1 using our protein expression services starting at $99 + $.30/amino acid in as fast as two weeks (includes the cost of DNA synthesis)
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