Nuclear phosphoprotein which forms a tight but non-covalently linked complex with the JUN/AP-1 transcription factor. FOS has a critical function in regulating the development of cells destined to form and maintain the skeleton. It is thought to have an important role in signal transduction, cell proliferation and differentiation (By similarity).

Belongs to the bZIP family. Fos subfamily.

374 amino acids

MMFTSFNAECDSSSRCSASPSDNVYYPSPAGSYSSMGSPQSQDLTDLTASSASFVPTVTAISTSPDLQWMVQPLVSSVAPSRRAHPYSPSPSYKRTVMRSGASKPHAKRGRVEQTTPEEEEKKRIRRERNKQAAAKCRNRRRELTDSLQAETDQLEAEKSSLQNDIANLLKEKERLEFILAAHQPICKIPSQMDSDFPVVSMSPVHAYLSTAASTQPQTSVPEATTVTSSHSTFTSTSNSIFGSNSDSLLSTATVSDSVVKMTDLESSVLEESLDLLAKTEVETVEVPDVNLSSSLYTAQDWEPLHATIGSSDFEPLCTPVVTCTPACTTITSSFVFTFPEAETFPTCCVAHRRGSNSNDQSSDSLSSPTLLAL

40.5 kDa

(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)

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