Acts as a transcriptional corepressor. Negative regulator of the transcriptional activity of tbx1 that plays a key role in pharyngeal development. Plays a role in the formation of the anteroposterior (AP) axis during embryonic development; required to establish the posterolateral border of the pre-placodal ectoderm (PPE) acting downstream of the retinoic acid receptor (RAR) signaling (By similarity).

Belongs to the ripply family.

170 amino acids

MDSSQYRLKATLTQLCLCSRGVRNVTSEHPEQQDSSLTLWRPWLLRAGDRELDGQQRRLGEADGDHRNTGPKGALGFQHPVRLYMPKSKTSEYLQHMGKKVLANFPVQATIHFYNDDSDSEEEEEDDEMEFYNYYQNCAANGVNSSRGSGDNYSVPGGPKRNISSHTGSA

19.1 kDa

(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)

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