Description
Intracellular mono-ADP-ribosyltransferase that may play a role in different processes through the mono-ADP-ribosylation of proteins involved in those processes. May play a role in the unfolded protein response (UPR), by ADP-ribosylating and activating EIF2AK3 and ERN1, two important UPR effectors. May also mediate mono-ADP-ribosylation of karyopherin KPNB1 a nuclear import factor. May not modify proteins on arginine or cysteine residues compared to other mono-ADP-ribosyltransferases.
Sequence
MQLSNRAAARESVSRDVLAADLRCSLFASALQSYKRDSVLRPFPASYARHDCKDFEALLADTGRLPNLKELLQSSRDTDKQTWDLVSWILSSKILTIHSAEKAEFEKIQQLTGAPHTPVPIPDFLFEIEYFDPANARFYETKGGRDLIYAFHGSRLENFHSIIHNGLHCHLNKTSLFGEGTYLTSDLSLALIYSPHGRGWQHSLLGQTLSCVAVCEVIDHPDVKCQTKKKDSKEIDRSRARIKHSEGGDVPPKYFVVTNNQLLRVKYLLVYSQKQPKRASSQLSWLCSHWFMVAMSLYLLLLLIVSVTNSSAFQHFWNRLKR
Simulated SDS-PAGE

(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)
Safety
Upon ordering, we will perform rigorous biosecurity and export control screening to ensure that order fulfillment is consistent with all legal and regulatory guidance.
Protein synthesis service