PKC is activated by diacylglycerol which in turn phosphorylates a range of cellular proteins. PKC also serves as the receptor for phorbol esters, a class of tumor promoters (By similarity).

Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.

658 amino acids

MSNSTLEMKGFARRGALRQKNVHEIKNHKFIPRFFKQPTFCSHCKDFIWGFGKQGFQCKVCSFVVHKRCHEFVTFQCPGLDPGVDSDDPRNKHKFKVHSYNSPTFCDHCGSLLYGLYHQGMKCGACDMNVHKRCQKSVPNLCGADHTERRGRIKVKAEVIGNKLQVTVAEAKNLIPMDPNGLSDPFVKLKLIPDQKRETKKKTRTIKGSLNPTWGESFDFNLEDTDRNRRLLVEVWDWDRATRNDFMGALSFGISELMKAGVDAWYKLLGQEEGEYYNVPAIAETESIDELTSNIKKLPMPTQEHVKPQNSNSMSGMGVVRASDFNFLSVLGKGSFGKVMLAEKKGTDELYAIKILKKDVIIQDDDVECTMTEKRVLGLPSKPAFLTALHSCFQTMDRLFFVMEFVNGGDLMFQIQKVGKFREPHAVFYAAEIAVGLFYLHSQGVIYRDLKLDNVLVDAEGHIKIADFGMCKEHMNEGDTTRTFCGTPDYIAPEIVAYQPYGKAVDWWAFGVLLYEMLAGQPPFDGEDEDELFQSIMEHVPSYPKSMSRESVTMCKGFLTKHPGKRLGSGPTGEQDIREHQFFRRIDWEKLANREIQPPFVPSVRNPRAAENFDPYFTKIPCALTPTDKLIIMNIQDEFQGFTFVNEVFDGYVRSLPS

74.9 kDa

(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)

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