Probable planar cell polarity effector involved in cilium biogenesis. Proposed to function as core component of the CPLANE (ciliogenesis and planar polarity effectors) complex involved in the recruitment of peripheral IFT-A proteins to basal bodies. May regulate protein and membrane transport to the cilium. May regulate the morphogenesis of hair follicles which depends on functional primary cilia (By similarity).

Belongs to the fuzzy family.

415 amino acids

MGDDGPGSTVHLLCLAASSGVPLFCRSSSGGAPSRQQLPFSVIGSLNGVHMFGQNLDVQLNSARTEDTTVVWKNFHDSITLIALSSEEGTSELKLERMLHMVFGAMVLIVGLEELTNIRNVERLKKELRASYCLIDSFLGNSELIGDLTQCVDCVIPPEGSVMQETLSGFAEATGTAFVSLLVSGRVVAATDGWWRLGMPEAVLLPWLVGSLPPQAARDYPVYLPHGSPTVPHRLLTLTLLRGLELCLLCGPRPPLGELDPQLLERWWQPLLEPLRACLPLGPRALPDGFPLHSDILGLLLLHLELRRCLFTVEPSKDKEPSPEQRRRLLRNFYTLVATTHFPPEPGPAEKQEDTVHPAQTPRACYLVLGPGMGWQLVAVQLGLRLLLLMLSPQTPTHGLRSLATHTLQALTPLL

45.4 kDa

(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)

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