May have a role in the processing of DNA double strand breaks (DSBs) prior to their repair by the non homologous end joining (NHEJ) pathway. Probably exhibits both exonuclease and endonuclease activity (By similarity).

Belongs to the DNA repair metallo-beta-lactamase (DRMBL) family.

639 amino acids

MSSFAGRMKEYPSISLDRFDRENLHARAYFLSHCHKDHMKGLKGPLLKRKLKFSLTVKLYCSYVTKELLLSNPRYAFWEDHIVPLELDSPTSISLIDESTGETEDVVVTLLSAGHCPGSVMFLFEGAKGTVLYTGDFRLAVGDAARMEYLHSGDRVKDIQSVYIDTTFFDPKYYQIPSREACLAGIQQLVQDWICQSPYHVVWLNCKAAYGYEYLFTNLGQEFNSQIHVNSLDMFKKMPEILCHVTTNRATQIHACRHPKDEEFFRANRLPCGSTAPDGIPLNIISIKPSTIWFGERTRKTSVVVKMGSSSYRACFSFHSSYLEVKDFLSYICPVNIYPNVIPLGKTVEDLTELLKPLCRKHCGREEIVYKPLGALKRTRKRSTSEGSDSDGDLFEEVSTAPRRRKITVSDLTTVAIRVRPHSANADSHDNDQTYSLIKLCPSAHTSNYMDCTESNDDDDDEDDAAEQTPAAAPPPSSTEKPCSKHTHSDSSLTSSTQPCWEKFFKAEVVLTDESELENSQNTQTLSTENTASQSPELFQDEDEDSSVHMSSSQSTHISDAGTESLSQVDTIMVQEDHSKACNLQHKTEEAAELKSDSQVSSDFELPPTPGSKVPQPEDLKELYRKLAAGEDVVARQIF

71.7 kDa

(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)

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