Description
Plays an essential role in growth and, with Dicer, also involved in microRNA (miRNA)-mediated translational repression. The RNA interference pathway is implicated in antigenic variation having a role in regulation of variant-specific surface protein (VSP)-coding gene expression. Several VSP genes are transcribed but only transcripts encoding the VSP to be expressed accumulate. Antisense RNAs corresponding to the silenced VSP genes are detected (By similarity).
Family
Belongs to the argonaute family. Ago subfamily.
Species
Giardia intestinalis (strain ATCC 50803 / WB clone C6)
Sequence
MVADVVTSRINFYPYTVLPSARPVYQYDLSIHISNQGYSLDNADSCRALERFCEQQDAALGNNLEHGLFYSLIIDFPSSDACPISSFYSQIDLGSRPITHTVEFLSTQKPRRRGGRVGGMRNNIAGPPITPVQATVKVTRVRQMDPTDLMSMKILLNILLRRTFESSLGMLNIRSGFYDLRNPSIHAIQIDGRGYDICWIPGFRLTTATLRGKLGLQILPETTKVRSKSMNELLTERRGNIHPSALAVITVMAMHNGKVFRVHSIVQGQTIVSPLANGNETDYFTYYSTRYRDKIDSAGLSLLRHNDYCNSVMQQDKFILKLTPLKRTQNGKVVRPCNVPSSLCIIISDNEIAPYGVSKLSTNRAAVALSTMSPDALLEKATAFAARLAEDTELQSLLGDYGFGFTSNPLELETFVCKPPKLMMDNTSRIVTIEDDSGGVFHNLLQSPGVSPIYYSNNNQPATGMPVWAIMVPRNLGNDYARRLRKELTERVRSLAGTTAPNIGDPPLIAVELSNQRREMYRVEPYKDAFKALLNKLRLEYKDARESEIVAKIQLVVIVIPGPKQDRGDLYKGIKQFYTHMGIVTQCLLAPKSSQNELQWYDQAVLRSVCQQIYAKAGGAVWAPVLPPQNVYSKSTMLCALDISRPKKTVGRPAEVPISTAGFISTYDGSFEYIYSQKKTLVPNRLNHGGELQQQTLMEAFIKNSCNVYLAFNNRILPDHIVIFRDGVSDSQISATLEVEIKSLYECLRQIYHKSNRPMCDLKVIVAQKTCAMRFSAVGGTVLRSGYYVINRSPDNRQQGSEFLMASQAIVHGTTPKPIRYKIIFDSMEASVDNDSFNQLIELTNAMAYGYVNWPQAISLPHVLHMAHHLSKFCGEVLRNGDDLFESCAIFGLQYRPFFI
Simulated SDS-PAGE
(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)
Safety
Upon ordering, we will perform rigorous biosecurity and export control screening to ensure that order fulfillment is consistent with all legal and regulatory guidance.
Protein synthesis service