Probably involved in the RNA silencing pathway. May bind to short RNAs such as microRNAs (miRNAs) or short interfering RNAs (siRNAs), and represses the translation of mRNAs which are complementary to them (By similarity).

Belongs to the argonaute family. Ago subfamily.

876 amino acids

MESQRMTWLYDRHHSLKHNKAERQAILSTYRLAKRPNLSSEGMIGESCIVRTNCFSVHLESLDDQTIYEYDVCVTPEVGINRAVIRELVKQQKDSGLGGRLPAYDGRKRLYTSGPLPFDSHRFLVLLDSIEDSPEESRHLRVRDFVVTLKFAAKISLWTLRKFRGGKPNRESRAALRALDVVLKELPTARYTQFAGSFYSPNLGECRQLCKVLESWRGFHQRIQATQMGLQLNIDVSSSVFIKPVPVVDYVAQLLNEDILLDRPLCSTEFLKIKEALEGLKVQINGILFNTYHVQDLVHQAASFPVNFSIQYPSLPCLKVAHFGETIFLPLEVCKIAEGQCHQKQLNAKHMAALLQVARQPPNERDYNILQTVHQNKYQEDPHAKEFGIKIEEKLVSIKSRILPAPWLKFHDSGETTEFLPQLGIWNMMHKKMINGGRVKSWACVNFCWSVREYAARNFCYDLGFMCRESGMVFSVKPVLPLVIAKPGCVESALRTLHDDVMDILRPQGRKLDLLIVILPNNNGSLYGDVKRICETDIGLISQCCLAKHVLKMNKWYLASVALKINAKMGGRNTVLVDALEMRLPHVRDTPTIVFGAHVTHPHPGKANSSSIAAVVASQDWPEVTKYAGLISVQACHQESIQGLFKVQDDPERGTTTSGMIKEHLMSFYRATKRKPGRIIFYRDGVSKGQLPQALMHELGAIKMACASMGPDYNPLVTYVVLQKCRHTRLFADYYNANTHDSTANIRAGTVVDSNICQPNQFDFYLCSHRSTQGTKRPRYYHVLWDENDFLAGSFQELTNYLCYTSATCTQSISVVAPVHYARLLSSRARCYIKPRSIGDSTSHTSLPSEEDSSAASETGSLLPIKDNLKGAMFFC

98.9 kDa

(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)

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