Description
Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB. Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation. Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently (By similarity).
Family
Belongs to the archease family.
Species
Methanosarcina acetivorans (strain ATCC 35395 / DSM 2834 / JCM 12185 / C2A)
Sequence
MPSQGKKYEYLEHTADIKFLAYGNTLKEVFENAALAMFNVIIDTGKVSGETAREVCLTSPDLESLLVDWLSELLYLFEVDEIVFWKFRVEEIREEEGEYSIKAVASGEQYYPESHPFETEIKAVTYNQLELEKTADGWKAQVVVDI
Simulated SDS-PAGE
![Western blot of MA_0265 recombinant protein](/recombinant/MA_0265-1.png)
(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)
Safety
Upon ordering, we will perform rigorous biosecurity and export control screening to ensure that order fulfillment is consistent with all legal and regulatory guidance.
Protein synthesis service