Ligand for members of the frizzled family of seven transmembrane receptors (Probable). Acts in the canonical Wnt signaling pathway by promoting beta-catenin-dependent transcriptional activation (PubMed:25451226). Developmental protein that promotes cell proliferation in the developing spinal cord (PubMed:25451226). Has a role in osteoblast function, bone development and bone homeostasis (By similarity).

Belongs to the Wnt family.

368 amino acids

MRGPALLLALRALCALSALRGTARAVNNSGRWWGIINVASSTNLLTDSGSVQLVLEPGLQLLSRKQRRLIRQNPGILHSVSAGLQSAVRECQWQFRNRRWNCPTSQGPNIFGKIVNRGCRETAFIFAITSAGVTHSVARSCSEGSIESCTCDYRRRGPGGPDWHWGGCSDNIDFGRLFGREFVDSSEKGRDLRFLMNLHNNEAGRMTVFSEMRQECKCHGMSGSCTVRTCWMRLPTFRAVGDVLKDRFDGASRVIYGNKGSNRASRVELHHLEPENPAHKPPSPHDLVYFEKSPNFCTYSGKMGTAGTAGRACNSSSPGLDGCELLCCGRGFRTRTQRVTERCNCTFHWCCHVSCLNCTNTQVLHECL

40.8 kDa

(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)

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