SPT factors 3, 7 and 8 are required for the initiation of Ty transcription from the delta promoter. SPT3 regulates Ty1 as well as the mating factor genes. Interacts directly with TATA-binding protein. It is likely to be required for normal TBP function at a subset of RNA polymerase II-dependent promoters.

Belongs to the SPT3 family.

328 amino acids

MSDKYKYRVEIQQMMFVSGENNEPPVETTSLIEDIVRGQVVEILLQATRTANCRGSKSIVPEDVIFLIRHDKAKVNRLRTYLSWKDLRKNAKDQDAQQAAAGGGAGDGSGPGGIDDDDAGKKDKDGAGVNMKVKKSSIKLPWELQFMFNEQPLENPDEDDMDDDEREANMATLKRLKMADDRTRGMTKEEYVHWSDCRQASFTFRKSKRFKDWSGISQLIDSKPHDDVIDILGFLTFEIVCAITETALKIKTRYERIRSMKTQSQPQEYSVGTTRRKKRLFDGPDNVVNPLKPEHIEEAWRVLQTVNMKHRALSNYKGGRLSSRTVIM

37.5 kDa

(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)

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