May negatively regulate the SNF1 kinase by promoting the interaction of the REG1/GLC7 phosphatase complex with the kinase. Deletion of SIP5 promotes resistance to artimisin, which is probably an indirect effect of an action on the electron transport chain (By similarity).

Belongs to the SIP5 family.

489 amino acids

MGNVPGKIDQEDSFNDVRPDSSYNTTSSNSVIKQYDEEASSRVRTRRTTSLVNNILNGNNARTKTGSHLSSTSRRKTSREKELAKEAHAKQLVVRCSETVDGGFLAPFGCYSFEKLDYDATVVKNLIIKRKLAPFYTPLQDFDESWTRDELIKIVDGLPLHDTFDENLEEFEDVPIGNLRKSTFNELIDKSLSKKEQRRMHAKIFRARLYKKRILWQENENETFLERKLEMKRIGSKSSNVEDNTSSQPRKNYHLPSDDLKYTLYKNGSECPICFLYFPGPFNYSKCCQQPICTECFVQIKRADPHFPHDEVDPTEPQTNDSEKDPNLLTSEPANCPYCATASFSITYQPPTNRETGIGGMPADSYVYKDAAISRADGGQPNIPAITSDTIRPDWEIKLNKERARLMRRSANATAIHISNRLIDPSHSTRRNTSHSITPIHDESTSASRSPEPTINELEDQMVREAIRLSLEDQDNRKKSKNRNTSLRP

55.8 kDa

(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)

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