Functions in the RNA-directed DNA methylation (RdDM) pathway. Acts as a pre-mRNA splicing factor, likely by affecting Pol V transcripts. Affects DNA methylation of transposable elements (TEs) and preferentially influences NRPD1- and ROS1-targeted loci.

786 amino acids

MDKERYSRSHRDDRDRDSSPDHSPQREGGRRRDRDVDSKRRDSDHYRSSRRGDREDERDRTKDRRGRSVERGEREGSRDREKHHHERSHEGSKEKESRSKRKDREEENGARDGKKKSRFADGNGERRSRFEDVAIEVENKDAQVSEGSGATNPTSGVTMGASTYSSIPSEASAAPSQTLLTKVSSISTTDENKASVVRSHEVPGKSSTDGRPLSTAGKSSANLPLDSSALAAKARKALQLQKGLADRLKNLPLLKKATKPTSEGSPHTRVPPSTTTPAVSTGTSFASTLPHTGLAGFGSIANIEAVKRAQELAANMGFHQDREFAPVINLFPGQAPSDMTVAQRPEKPPVLRVDALGREIDEHGNVISVTKPSNLSTLKVNINKKKKDAFQILKPQLEADLKENPYFDTRMGIDEKKILRPKRMSFQFVEEGKWTRDAENLKFKSHFGEAKAKELKVKQAQLAKANDDINPNLIEVSERVPRKEKPKEPIPDVEWWDANVLTNGEYGEITDGTITESHLKIEKLTHYIEHPRPIEPPAEAAPPPPQPLKLTKKEQKKLRTQRRLAKEKEKQEMIRQGLLEPPKAKVKMSNLMKVLGSEATQDPTKLEKEIRTAAAEREQAHTDRNAARKLTPAEKREKKERKLFDDPTTVETIVSVYKIKKLSHPKTRFKVEMNARENRLTGCSVMTDEMSVVVVEGKSKAIKRYGKLMMKRINWEEAERKEGNEDEEEEVNGGNKCWLVWQGSIGKPSFHRFHVHECVTESTAKKVFMDAGVVHYWDLAVNYSDD

88.6 kDa

(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)

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