Description
Required for proper folding and/or the stability of a subset of proteins in the endoplasmic reticulum. Component of glycosylphosphatidylinositol-mannosyltransferase 1 which transfers the first of the 4 mannoses in the GPI-anchor precursors during GPI-anchor biosynthesis. Probably acts by stabilizing the mannosyltransferase GPI14 (By similarity).
Family
Belongs to the PIGX family.
Species
Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)
Sequence
MSVQTIQSESFIEEKRRITVLLDRDGRSVEEKVVNRDGVITIPNQSGHVQDRAVLFVPQLASRPDFIHISWKRNAEADITPIKSYIPYGFNIFTNSSGSIAKFIDTPVGKVYYSDTFEDNALSKWFPPEFVDQLLRYSEDNDLDITVTRGRVEVNRYYELTDDNLFPLNGTESVKTEAGIFQVDTEDDTDTSLSGLRCTWHTGSGALNKCQRTLFFYNQIYADKSSLSEVSLTLSEPVNLHPVVQIDLTSKRPIHNCEYYAYFNLPKYFFIDQFQSIPTLLFGEHDLELPEYKLSGFGSISLFTLQPGSINEVTLHSRYIKPTNDGSAFFEAAFTPQVFYACDTSIELTKRSPFYTGKIGYEHFFTDNTKFYYLNSTKMTINLPKLDSSDNLCIQLFTLGLVLFSVLYLIRKLF
Simulated SDS-PAGE
(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)
Safety
Upon ordering, we will perform rigorous biosecurity and export control screening to ensure that order fulfillment is consistent with all legal and regulatory guidance.
Protein synthesis service