Lectin which functions in endoplasmic reticulum (ER) quality control and ER-associated degradation (ERAD). May bind terminally misfolded non-glycosylated proteins as well as improperly folded glycoproteins, retain them in the ER, and possibly transfer them to the ubiquitination machinery and promote their degradation. Possible targets include TRPV4 (By similarity).

Belongs to the OS-9 family.

667 amino acids

MAAETLLSSLLGLLLLGLLLPATLTGGVGSLNLEELSEMRYGIEILPLPVMGGQSQASDVVIVSSKYKQRYECRLPAGAIHFQREREEETPAYQGPGIPELLSPMKDAPCLLKTKDWWTYEFCYGRHIQQYHMEDSEIKGEVLYLGYYQSAFDWDDETAKASKQHRLKRYHSQTYGNGSKCDLNGRPREAEVRFLCDEGAGISGDYIDRVDEPLSCSYVLTIRTPRLCPHPLLRPPPSAAPQAILCHPALQPEEYMAYVQRQADSKQYGDRAIEGRQDPDPPVWSETKPGVVPPKKAGASPAKENSKESDFWKMLHEPEEQPPEKEETQAEEQEPNLEATDPPPTSPDDFQNNVQVKVIRSPADLIRLIEELKGGTRKGKPNTGQEQPGDSATEVPSREPEMKEKGDPEQQNEVEEEEDDEDEDEDEDERQLLGEFEKELEGILLPSDRERLRAEVKAGMERELENIIQETEKELDPDGLKKESERDRAILALTSTLNKLIKRLEEKQSPELMKKHRKRRVVPKKPPPSPQSTEEDPEHRVRVRVTKLRHGGPNQDLTVLEMKRENPQLKQIEGLVKDLLEREGLTAEGKIEIKIVRPGTEGTEEDARWLTDEDTKNLKEIFFNILVQGAEEAQKERQRQKELESNYRRVWGSPGGEGTGDLDEFDF

75.8 kDa

(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)

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