Lectin involved in the quality control of the secretory pathway. As a member of the endoplasmic reticulum-associated degradation lumenal (ERAD-L) surveillance system, targets misfolded endoplasmic reticulum lumenal glycoproteins for degradation (By similarity).

Belongs to the OS-9 family.

520 amino acids

MIRRIRTLTPLLVLACAGSGAWASKKAFNIQDDLLAYPQFQVFFPDEYILDARARELLQNQQESSSASADKTFSEGNDAQVYLGSRKDQSEDVNKETIEGSGFTYEEMLLEGQRYLCSIPQVDNGNRDQTNGAESTSKEDEQREIARATDRGLELLREMEGKCMYYISGWWSYSFCYKKQIKQFHALPSGPGVPNYPPIEDSTTHSFVLGRFPNSGDDEDLEGDAEHKKTTTDVAELQTKGGSRYLVQRLGGGTKCDLTGKDRKIEVQFHCHPQSTDRIGWIKELTTCSYLMVIYTPRLCNDVAFLPPQQDEAHAIECREILSEEEVSDWEANREYHLAQQLVESAITPEFPVVGDIEVGAHKWVGSEGKQIEKGRVASIGEEKIEVVAKRQNGEITRLSKEELKKYGLDPEKIETLKSRLEELAKGKDWTLEIVESNGERGLVGTVDSNDDEKEDHAAQGSISQPAQGTTADKGESNAETGEEKKKADEKIDHYEPEKSGPTTDDADDGSEEIFFKDEL

58.3 kDa

(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)

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