Transcription factor which plays a key role in defining the composition of the RNA polymerase II (RNAPII) elongation complex and in modulating the production of mature mRNA transcripts.

Belongs to the IWS1 family.

836 amino acids

MEADNYSPEHSDDGGATPVQDERDSASDDEGNEQRSEPGSPEHQSEDEHSDVEDHKHSSDSGSDNEKGTEHDSEDEHRPRNSSDLENHDASDSENEESHNRIASDSEDDGRRQKNSDSDRSPVKGAASDSDEEPVRHSASDSEDDVPRKQQANDSEDERHIKKTASDSEDEAPAKHRVSDTEDKAPPKQVASDSEDEASPKQVASDSKDEAPPKHAASDSEDEAPPKLAGSDSEDEAPAKRKVSSSEDETPSKHAVSASKVKKSVGSEDKTRGKRAIIDSDDDDDDDVPVKRAASDSEEETHPKGKASDSEDEAPSKQPSDSEEETPAKVAANDSEDEFPRMKRKIVSSDDSDDEDDRKPLQKKKKSPRRSSESDSSDKVDGKKLQASESDEEGEKASKKKKSNIVSDSEDEDAADKSGNKKSRILSDGEDSDSDAASEKPKQKKKKSASSDSEEEDERKSKTETKSADKLFGSESDSENEEENLIADIFGESGDEEEEEFTGFNQEDLEGEKTVTSVNRQQAAAADSDSDDDMKSGKMGDYKSDFDLMLERKKSMSGKQRRNRDGGTFISDADDVVNAMIMKMTEAAEEDRNLNSSKKPALKKLTLLPTVVMHLKKQDLKETFIDSGVMSAIKEWLTPLPDRSLPALKIREELLKILQELPSVSQETLKHSGIGRAIMYLYKHPKESRPNKDIAGKLINEWSRPIFGLTSNYKGMTREEREQRDIEQMPQRRRMSSSGGQTPRRDLDKVLTGEEKALRPGEPGFCARARVPLPSNKDYVVRPKWNVEMETSQYQGSAKKGVSRIDKQMRKFVDIKKKNRFGHAVKISIEGNKMPL

92.7 kDa

(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)

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