Description
Interacts with the host phosphatase PP1 catalytic subunit (PPP1CB) and recruits it to dephosphorylate EIF2S1/eIF2alpha and therefore restores the host translation that has been shut-down by the host. Also inhibits the EIF2S1/eIF2alpha-ATF4-DDIT3/CHOP pathway.
Family
Belongs to the asfivirus DP71L family.
Species
African swine fever virus (isolate Pig/Kenya/KEN-50/1950)
Sequence
MSRRNKKRSRRRRKKPLNDIQPGPSKSSAQDEPIKSVSHHLSKIGTNPTLAFILGGNEDLSDDSDWDENFSLENTLMPLNEVSLNDKHNSKHFNKGFDNNTALHEVNTKWEAFYSSVKIRQRNVKVHFATDDILVDVREADDIDRKGPWEQAAVDRLRFQRRITDTEEILSTVFLRKKLNPMEHE
Simulated SDS-PAGE

(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)
Safety
Upon ordering, we will perform rigorous biosecurity and export control screening to ensure that order fulfillment is consistent with all legal and regulatory guidance.
Protein synthesis service