Probable microtubule plus-end tracking protein that promotes the stabilization of dynamic microtubules. Required for the formation of mitotic and meiotic spindles. Specifically promotes the polymerization of kinetochore-bound microtubules. Also required for cytoplasmic streaming (By similarity).

Belongs to the CLASP family.

single

791 amino acids

MSRVVSRTVPGGACVVNKDDFLKSFNDVDKVSVSSLADAKSKFDQVIAILSKSQEDWNKRRTQLQIIRSIVINCEDVIGRDQLLGQLVRLADCLDLSVKDLRSQILREAAITCSFLFEKYGNDVHQIAERCLPTAFSQLAVSTKVMATSGATLTLFLVQYVQTKQIFTCLTTYSTSKDKNQRRQLCVLLEIVIEHWNDKLKKSILPQIMELIKSAISDADPETRAAGRKAFNKLDAIHSEEADKLFASVDANKQKMLRASDAASSSTSVNSERGSAPFRSKLSAGSVGGMRNVPNISSKFLAQRSASAIDTKQVTRMTTSVSRTPNTRPMTTRTLSKVDTSPGGSKFARPTVGTLGPRTTSNLRARGSVPTSQPGSRNGSPPRRPSTTGTLPMEMQRVKSNLGSSSFVSSLTPDQAESLQKAMNTAKESLGQPSRTEDDEFLLPKRKPKTPQKSAVDISRVEAVIRACVSTSANEKRDGIKMLSIIVSEPNLSQIELKNIGQVLNRLLGEATNPVVLESVASFVKAHHSRLSEWLKLGLGKMFAKKGSEMMPIMKKHIVTTINAILSSFDPALQLKATCELMCDPIHLLSPKARVALLEYLTDLLEKHMERGSPFNTKEVKATILKMFSWMSDQRNMQQIVPHGEKVLCGLFALNAADFSALFNDFNPDYREWAYRILQAHGHNQHAPAPESPSPVRDQQVRANISNTAAQIEDFVVARNFELSAEKSPTSRGMLTSGFKRTDAEPLRPLESDMNTQRMDDISINESFDRLKVRILETTGFYAAFKVDFQE

87.5 kDa

(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)

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