Description
Functions as 15-oxo-prostaglandin 13-reductase and acts on 15-keto-PGE1, 15-keto-PGE2, 15-keto-PGE1-alpha and 15-keto-PGE2-alpha with highest activity towards 15-keto-PGE2. Overexpression represses transcriptional activity of PPARG and inhibits adipocyte differentiation (By similarity).
Family
Belongs to the NADP-dependent oxidoreductase L4BD family.
Sequence
MIVQRVVLNSRPGKNGHPVAENFRVEEVNLPDCVNEGQVQVRTLYLSVDPYMRCRMNEDTGSDYITPWQLSQVVDGGGVGIIEESKHTNFMKGDFVTSFYWPWQTKVILDGNILEKVDPQLVDGHLSYFLGAIGMPGLTSLIGVQEKGHITAGSNQTMVVSGAAGACGSLAGQIGRLLGCSRVVGICGTPEKCLFLTSELGFDAAINYKEGNVAEQLHKLCPAGVDVYFDNVGGDISDTVISQMNQNSHIILCGQISQYNKDVPYPPPLPPAIEAIQKERNITRERFLVLNYKDKFEFGILQLSQWFKEGKLKIKETMINGLENMGAAFQSMMTGGNIGKQIVCISGDTSL
Simulated SDS-PAGE
(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)
Safety
Upon ordering, we will perform rigorous biosecurity and export control screening to ensure that order fulfillment is consistent with all legal and regulatory guidance.
Protein synthesis service