Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).

Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.

478 amino acids

MGKKNKQFVEKITAMEDDFAQWYTDVVKQADLVDYGQVRGTMIIKPYGYAIWENIKNELDRMFKETGHTNVAFPLFIPESLLQKEKDHVEGFAPEVAWVTHGGEEELTERIAVRPTSEVLFCDYYSNNIHSYRDLPKLYNQWGNVVRWEKTTRPFLRSSEFHWQEGHTAHATDEEATEETNRMLETYAKLVEEYLAVPVLKGRKTDKEKFAGAKFTLTIEALMHDGKALQSGTSHHFGTGFAEAFDINYLDKDGKSQFVHQTSWGLSTRIMGALIMVHGDNRGLVVPPKIAPTQAMIVPIAQHKEGVLDKAYELRDKLAKVARVDIDGSDKMPGWKFNEYEMKGIPVRVEMGPKDIEKEQVVLVRRDTGEKEFVPVAEVETRLVELLDEVQSNLYQRALDHRNEMTTVAKDMDEFKEKIEEGGFIKAMWCGDVSCEESIKEETTATSRCIPYEEEKVADTCVCCGKKAKELVYWARAY

54.8 kDa

(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)

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