Receptor for prokineticin 1. Exclusively coupled to the G(q) subclass of heteromeric G proteins. Activation leads to mobilization of calcium, stimulation of phosphoinositide turnover and activation of p44/p42 mitogen-activated protein kinase. May play a role during early pregnancy (By similarity).

Belongs to the G-protein coupled receptor 1 family.

393 amino acids

MEITMGVMDENATNTSTNYFPLLDPLGAQAASFPFNFSYGDYDMPLDEDEDMTNSRTFFAAKIVIGMALVGIMLVCGIGNFIFIAALARYKKLRNLTNLLIANLAISDFLVAIVCCPFEMDYYVVRQLSWEHGHVLCASVNYLRTVSLYVSTNALLAIAIDRYLAIVHPLRPRMKYQTATGLIALVWVVSILVAIPSAYFTTETVLVIVKSQEKIFCGQIWPVDQQIYYKSYFLFIFGIEFVGPVVTMTLCYARISRELWFKAVPGFQTEQIRKRLRCRRKTVLVLMCILTAYVLCWAPFYGFAIVRDFFPTVFVKEKHYLTAFYVVECIAMSNSMINTVCFVTVKNNTIKYFKKIMLLHWKASYNGSKSSGDLDLKTTGVPATEEVDCIGLK

44.6 kDa

(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)

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