Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG (By similarity).

Belongs to the profilin family.

133 amino acids

MSWQTYVDDHLMVDFEGQGQHLAAAAILGHDGSVWAQSPHFPKFKPEEITNIMKDFDEPGFLAPTGLFLAGIKYMVIQGEPGAVIRGKKGSGGITIKKTNQALIFGLYEEPVTPGQCNMVVEKIGDYLVDQGY

14.6 kDa

(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)

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