Description
Catalyzes the methylthiolation of N6-threonylcarbamoyladenosine (t(6)A), leading to the formation of 2-methylthio-N6-threonylcarbamoyladenosine (ms(2)t(6)A) at position 37 in tRNAs that read codons beginning with adenine.
Family
Belongs to the methylthiotransferase family. CDKAL1 subfamily.
Species
Archaeoglobus fulgidus (strain ATCC 49558 / VC-16 / DSM 4304 / JCM 9628 / NBRC 100126)
Sequence
MRVAIETYGCTTNQADSDIMRGFLSGEFELSSVEDAEVVIINSCGVIDFTERKIIRRMLDLKREGKKVVLAGCLTRISKEALSVADSALSPDNLDMVVDAVYSALNGRKLFTERRFIDKAEFSHLKCRLRENAIAIVSISEGCLGKCSFCATKFARGRLRSFSMDAIVREAERAVRAGYREIQLTSQDTGAYGMDKGRAMLPELLRKISEIEGEFRVRVGMMNPQHAVRMLDELINAYSSEKIYKFLHIPVQSGDNRILEDMKRNHTVEDYVEVVEAFRNSFDDVLISTDIIVGFPTETEEAFWKSYELIKETRPDIVNITRYSARKGTPAARLRDIPGWIKKERSRKLTDLMRKIGLENNKRFVGKKLRVLVTKEGKNGRNLARMNSYRAVVTEGAVGEFVEVKIKDCRFNYLIGQLAAEQPQ
Simulated SDS-PAGE

(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)
Safety
Upon ordering, we will perform rigorous biosecurity and export control screening to ensure that order fulfillment is consistent with all legal and regulatory guidance.
Protein synthesis service