Probable RNase involved in rRNA stability through maturation and/or degradation of precursor rRNAs. Preferentially cleaves UA sequences in the 5' precursor region of 5S rRNA (PubMed:28978920). Binds to RNA in loop regions with AU-rich sequences. Binds to the consensus sequence GGC(U/A)(U/A)U(U/C) in vitro (PubMed:12614195).

Belongs to the FAU-1 family.

469 amino acids

MSTESEIAVRIRGIYSTALTKLLMDRGFKIVQPSDVIAERFGIEKSYEDFDVDIYDKNHGVTIVGTKVEAVKKVFEEEFIDVFFRKLPYKLHGIYKGLVVKRDDRFVYVDIGNVIGTVLIEELPDAAEGDEVVVQVKKHNVLPHLSTLITIPGDYAVLIPKPIGVQRHVKISRKIKDPEERERLRILGLSVDLGEWGVLWRTAAAYKDWNTLRDELVRLSKIADKLKEAEKFSAPAEIIEGREIYEIEFGGGVKKKLDEIRNEVVPTIEGHHQFKSYDPEFTLAVDVAEGILAKLPSQRQKISKGFLEAIITSKGPKVGWIFTLNHVKPDGQIIKIGPGEVIEVSTDPLKVTIKRYLRPGKFYDGLEVPIESGDYAITEIEAGKWWFVHRYYDKDGNLKGEFYNINTPVEIYPDKARYVDLEVDIVRWPDGKKEIIDKEKLKEHYEEGIISEKLYKATLRIAQEVYDRL

53.7 kDa

(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)

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