Central component of the receptor complex responsible for the recognition and translocation of cytosolically synthesized mitochondrial preproteins. Together with TOM22 functions as the transit peptide receptor at the surface of the mitochondrion outer membrane and facilitates the movement of preproteins into the translocation pore. Directly involved in the pore formation (By similarity).

Belongs to the Tom40 family.

310 amino acids

MEGFSPPINTAQVDAKTKLDEKVDYSNLPCPVLYEELNREATMALKPELFEGFRLDYNKSLNQKFFLSHSILMGPTEVPNPTPSSEIIKIPTANYDFGAGFIDPKLYLIGRITTDGRLNARAKFDLTDNFSVKANALLTDEEDKSQGHLVIDYKGSDYRTQLQLGNNSVYAANYIQHVTPHLSLGGEAFWLGQQLMSGVGYAARYETDKTVASGQIASTGVAVMNYVHKVSEKLSFATDFIYNYLSRDVTASVGYDLITRQSRLRGKVDSNGVVAAYLEEQLPIGLRFLLSAEVDHVKKDYKFGFGVNAF

34.5 kDa

(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)

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