Catalyzes the hydrolytic deamination of adenosine. Plays an important role in purine metabolism and in adenosine homeostasis, and may thereby contribute to cellular signaling events (By similarity).

Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

772 amino acids

MIENNKEITLDIIKLLPKAELHRHLDGSIRISTLLELAKEQNVELPTYDQNELAKLIHKDENCSGLVNFLEAFQYTCSVLQHAYAITRVFYEMCEDAVADGVSYLEIRFSPVLHTSFGLSLSEVMEAVCDGMAIAELNLPIKARIIVCGLRHLDPSISKDLAEITWRYRHKGAIAFDLAGPEDGFSSKHHKEAFSIIRNKGINCTLHSGEDSNWTSVADSIHHCGAHRIGHGIAIQQNEELLNHVVNRRIPIECCITSNYQIKAISNASEHPIRKYFDSGAIVSICCDNCTMSNITLSGEYKLAIDTFNFKVEEVIRLIDYSFASSFIDPPLKINIRRESFKKALKIFQTNGYDISGVIENKFYYFEEIGLDVELEIQNNLANNFSLGKNVIRNYPQITLELLENLPKSDLHCRFDGGVSIEQIWNEVQLLGIDKCEKSKQEFLKKLSSKHLACYANFKDFKEFKSLIQSSSHTPQTIRLSKEIINLLLQTPEQINRAFDDIIKVALKDKVQYLELMIRPNSHSRNGLTKEQVLALIIENKDKWEKSSSIKIGLVVFSSSTSDDPIETLDSARLAIANRNSGVIGFGIFGADPISPTESRHFSQTFSLLKENNFNLVQFAGKSDVESLISTIHCSGSTRLSGAFQSHKIPRLMSYLGNYSIPVEISLTEKLKSFTSDDLSFTTPIRHLLDGKCPVVICSFRSSLYPYSRSKMYYKIVKNAKLDFKQVVRLLKNPFAYNFQSHQQRIELVQQFNKLSKEYLNSVNINYSNIII

87.5 kDa

(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)

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