Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament (By similarity).

Belongs to the ARPC2 family.

304 amino acids

MILLEINNRIVEETLTVKFKNAIAGNKAESIDVTVADFDGVLFHISNINGDKTKVRTSISLKFYKQLQEHGADELLKREYGDLLVAPEDGYNVSVLVDLENIPENWEETVRKIGLLKRNCFASVFEKYFDFQSQGEGEGEGQKRAVINYRNDETMYVEAKPDRVTVVFSTIFRDEDDVVLGKVFMQELREGRRASHTAPQVLFSHREPPLELANTGARVGENIGYVTFVLFPRHTAKETRDNTINLIHMFRDYLHYHIKCSKAYIHSRMRAKTTEFLKVLNRARPEPKITEKKTITGRTFIRKE

35.1 kDa

(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)

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