Involved in translational control mechanisms operating in early stages of oogenesis. Required maternally in many stages of oogenesis, including cystocyte differentiation, oocyte differentiation, and specification of anterior-posterior polarity in the developing cysts. Essential for the formation and/or structural integrity of perinuclear nuage particles during germ cell formation.

Belongs to the DEAD box helicase family. DDX4/VASA subfamily.

703 amino acids

MSDDWDETDAAPASDWNIESFGLPTSFGSTKKTCNTGNAFNDGEGGFDEGSQSNFDDPFRSGGGGFGGRGRGGPRACFKCGDEGHMARDCPSASDSRGNRTNNRRQDNWGGGSSSKPANGEPFGFGSAFGDNQESDPFGATESSGFGFGSGSGSRGGRRNDGGRGCFKCGEEGHMSRDCPSGGGRNKGCFKCGQEGHNARDCPNPGEGSEEKKPRAPLYIPADVNEDELFVMGIEAGSNFDAYANVPANVSGAEPIQPAAESFQSMNLRPLLLENIVKAGYGCPTPVQKYTIPNVMNGRDIMACAQTGSGKTAAFLLPMLHYILDNNCPSNAFEEPAQPTGLVICPTRELAIQIMREARKFSHSSVAKCCVAYGGAAGFHQLKTIHSGCHILVATPGRLLDFLEKGKIVFSSLKYLVLDEADRMLDMGFLSSIKTVINHKTMTPTAERITLMFSATFPHEIQELASAFLNNYLFVVVGTVGAANTDVKQEVLCVPKFEKKAKLVEMCEEILISADDEKILVFVEQKRVADFVGTYLCEKKFRATTMHGDRYQAQREQALSEFRTGVHNILVATAVTARGLDIKGIGVVVNYDLPKDIDEYVHRIGRTGRLGNRGLSISFYDDETDACLTKDLVKVLSEANQTIPDWLTQKANASGHAQTYHGSGLFASSDIRSKNGGGRGWEKNQASSFLGGPSESNVDEEWD

75.7 kDa

(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)

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