Description
Potential catalytic subunit of the gamma-secretase complex during spermatogenesis, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors (lin-12 or glp-1) (Probable). Involved in spermatid formation during meiosis II (PubMed:9819355, PubMed:29879108). May be required for proper localization of macromolecules that are subject to asymmetric partitioning during spermatogenesis (PubMed:9819355).
Family
Belongs to the peptidase A22A family.
Species
Caenorhabditis elegans
Sequence
MDTLRSISSELVRSSQLRWTLFSVIANMSLTLSIWIGVYNMEVNSELSKTYFLDPSFEQTTGNLLLDGFINGVGTILVLGCVSFIMLAFVLFDFRRIVKAWLTLSCLLILFGVSAQTLHDMFSQVFDQDDNNQYYMTIVLIVVPTVVYGFGGIYAFFSNSSLILHQIFVVTNCSLISVFYLRVFPSKTTWFVLWIVLFWDLFAVLAPMGPLKKVQEKASDYSKCVLNLIMFSANEKRLTAGSNQEETNEGEESTIRRTVKQTIEYYTKREAQDDEFYQKIRQRRAAINPDSVPTEHSPLVEAEPSPIELKEKNSTEELSDDESDTSETSSGSSNLSSSDSSTTVSTSDISTAEECDQKEWDDLVSNSLPNNDKRPATAADALNDGEVLRLGFGDFVFYSLLIGQAAASGCPFAVISAALGILFGLVVTLTVFSTEESTTPALPLPVICGTFCYFSSMFFWEQLYG
Simulated SDS-PAGE

(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)
Safety
Upon ordering, we will perform rigorous biosecurity and export control screening to ensure that order fulfillment is consistent with all legal and regulatory guidance.
Protein synthesis service