Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

Belongs to the polyribonucleotide nucleotidyltransferase family.

698 amino acids

MNPIVKSFEYGQHTVTLETGVIARQADAAVLASMGDTTVLVTVVGKKVADLSRDFFPLTVNYQEKTYAAGKIPGGFFKREGRPSEDETLIARLIDRPIRPLFPNGFKNEVQVIITVVSVDPQIEPDIVSMIGTSAALAISGIPFSGPLGAARVGYINDEYVLNPTVDQLATSSLNLVVAGTKAAVLMVESEAKALAEEIMLGAVTYGHDQQQVVVDAIAEFKAEAGKPTWDWTAPVQDQALVAKIKELAEAGMTEAYQIEVKQDRYVQVGIVKAAAKAALVAENPDVDTREVDNLLGSLEKSVVRGRIISGKPRIDGREPDMIRALSVLAGVLPRTHGSSLFTRGETQALVTCTLGTERDAQKIDSIMGERTNRFMLHYNFPPYSVGETGMVGSPKRREIGHGKLAWRGMNAVMPSAEEFPYSIRVVSEITESNGSSSMASVCGTSLALMDAGVPIKTSVAGIAMGLVKEGDDFVVLSDILGDEDHLGDMDFKVAGTRDGITALQMDIKIEGITKEIMDIALQQAYGARVHILNVMDQAIGTHRGDISAHAPRITTIKINPEKIRDVIGKGGAVIRALTEETGTTIELDDNGTVKIASSNGEATKEAIRRIEEITAEVEVGRIYNGKVIRIVDFGAFVNILPGKDGLVHISQISDERVANVSDHLEMNQEVAVKVMEVDRQGRVRLSIKEAQAKETAE

75.2 kDa

(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)

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