Protein expression services for Dhc1 | Polyketide synthase-related protein Dhc1
Description
Polyketide synthase-related protein; part of the gene cluster that mediates the biosynthesis of 10,11-dehydrocurvularin, a prevalent fungal phytotoxin with heat shock response and immune-modulatory activities (PubMed:26493380). The highly reducing polyketide synthase Dhc3 is responsible for biosynthesis up to the tetraketide stage (PubMed:26493380). The non-reducing polyketide synthase Dhc5 then conducts four additional chain extension cycles, producing the unreduced part of the nascent octaketide from C-1 to C-8 in 10,11-dehydrocurvularin (PubMed:26493380). The role of Dhc1 in 10,11-dehydrocurvularin biosynthesis has not been identidied yet (PubMed:26493380).
Species
Alternaria cinerariae
Length
477 amino acids
Sequence
MPKTPNGKLDRKSIAALLLRNAKRDMNGVVNDVEKMTVREGELRLLWERVLPTLGDLRLGPSSDFFMCGGNSMLLMKLQKAIKETTGIRVSTKDLYESSTLRAMTHCVFDRANRADDDAAPIDWAVETSLPASLQTQIQDLATSSPPEAGGHGTNGTEVLLTGATSFLGSHLLRSLLSSPRVKKVHCVAVPADEQATLFSHDTRIVCYSGTLLSPTLGVTPQERRTLEQSVHVIVHAGAHGHCLNRFDSLRAPNLQSLHFLATLALPRCVTILFLSSSRVVLLSGDTAPAPASMRSYPPAVDGKDGYTASKWAGEVFLENLVAHVENVASSASSPSVFWRSSLNVEVHRACTLVSESAPNSDAMNAILRHSLDMRCAPRLERAEGYLDFAPMESIVAKITVHAVEMATAVQQQQQQQQRQSQPPRDDAADGSPTERARGLRIAITLAVSSRPWATLGRIWRGRMVGDPKNWIYKSGL
Mass
52 kDa
Simulated SDS-PAGE
(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)Safety
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Protein synthesis service
Make Dhc1 using our protein expression services starting at $99 + $.30/amino acid in as fast as two weeks (includes the cost of DNA synthesis)
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