Flavoenzyme involved in polyamine back-conversion (PubMed:21796433). Catalyzes the oxidation of the secondary amino group of polyamines, such as spermine (PubMed:21796433). Substrate preference is spermine > thermospermine > norspermine (PubMed:21796433). No activity detected when putrescine, spermidine or N(1)-acetylspermidine are used as substrates (PubMed:21796433). Plays an important role in the regulation of polyamine intracellular concentration (Probable).

Belongs to the flavin monoamine oxidase family.

487 amino acids

MDPNSLKTGGLLLPTIERQCASPPSVIVIGGGISGVAAARALSNASFEVTVLESRDRVGGRVHTDYSFGCPIDMGASWLHGVCNENSLAPLIGYLGLKLYRTSGDNSVLYDHDLESYALFDKAGHQVSKETVAKVEETFERILDETVKVRDEQEHDMPLLQAISLVLERHPHLKLQGIDDQVLQWCVCRLEAWFAADADEISLKNWDQEHVLTGGHGLMVNGYYPIIQALAQGLDIRLNQRVTKIARQFNGVTVTTEDGTSYSADACIITVPLGVLKANIIKFEPELPSWKSSAIADLGVGIENKIAMHFDTVFWPNVEVLGMVGPTPKACGYFLNLHKATGNPVLVYMAAGRFAQEVEKLSDKEAVDLVMSHLKKMLPDATEPTKYLVSRWGSDPNSLGSYSCDLVGKPADVSARFAAPVENLYFAGEAASADHSGSVHGAYSSGIAAADECRKRILMQKGIPDLVQVKAYEEMAGVIAPLQICRT

52.9 kDa

(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)

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